Intraoral splints are effective in migraine prevention. In this review, changes in the quality of life of migraineurs treated with a palatal nonoccluding splint were measured
The timing of migraine pain is not linked to vasodilation.1 The fact that vasodilatation in the absence of neurogenic inflammation is not painful makes it clear that vasodilatation is not sufficient, and may not be necessary, for migraine pain.
The authors present the results of the elegant experiments of Lambert et al. as evidence supporting their claim that the trigeminovascular system does not require a peripheral sensory input to be activated.