Paraesthesia of the lowe lip is well recognised as one of the symptoms of the displaced fractures, extensive infections, and malignant neoplasms of the mandible.
The timing of migraine pain is not linked to vasodilation.1 The fact that vasodilatation in the absence of neurogenic inflammation is not painful makes it clear that vasodilatation is not sufficient, and may not be necessary, for migraine pain.
The authors present the results of the elegant experiments of Lambert et al. as evidence supporting their claim that the trigeminovascular system does not require a peripheral sensory input to be activated.
